Predicting MicroRNA Target Genes and Identifying Hub Genes in IIA Stage Colon Cancer Patients Using Bioinformatics Analysis

Table 4

KEGG pathway analysis of target genes associated with IIA stage colon cancer.

Regulated	Category	Term	Count	%	P-Value	Fold Enrichment	FDR
Up	KEGG_PATHWAY	hsa04360:Axon guidance	21	2.24	7.30E-06	3.173885	0.009462
Up	KEGG_PATHWAY	hsa04010:MAPK signaling pathway	31	3.30	1.94E-05	2.333442	0.025073
Up	KEGG_PATHWAY	hsa04144:Endocytosis	31	3.30	2.43E-05	2.306309	0.031476
Up	KEGG_PATHWAY	hsa05205:Proteoglycans in cancer	26	2.77	3.53E-05	2.495278	0.045696
Up	KEGG_PATHWAY	hsa04068:FoxO signaling pathway	20	2.13	5.61E-05	2.864842	0.072721
Down	KEGG_PATHWAY	hsa05200:Pathways in cancer	108	3.73	1.58E-10	1.810230026	2.10E-07
Down	KEGG_PATHWAY	hsa04510:Focal adhesion	66	2.28	1.44E-09	2.110470443	1.90E-06
Down	KEGG_PATHWAY	hsa04151:PI3K-Akt signaling pathway	91	3.14	4.76E-08	1.737500173	6.31E-05
Down	KEGG_PATHWAY	hsa05222:Small cell lung cancer	32	1.11	9.87E-07	2.479896821	0.001306893
Down	KEGG_PATHWAY	hsa04550:Signaling pathways regulating pluripotency of stem cells	44	1.52	2.04E-06	2.070271006	0.002694908