Research Article

The Association of Serum hsCRP and Urinary Alpha1-Microglobulin in Patients with Type 2 Diabetes Mellitus

Table 3

The comparison of hsCRP and each urinary protein parameter in different groups.

GroupCase numberhsCRP (mg/L)UA1MG (mg/gCr)UACR (mg/gCr)UIGG (mg/gCr)UTRF (mg/gCr)

Group by UA1MG
 UA1MG ≤10(mg/gCr)2541.00(0.49-2.80)5.78(4.12-7.91)9.04(4.98-19.87)4.13(3.01-6.30)2.30(1.50-3.33)
 UA1MG >10(mg/gCr)2661.49(0.60-4.19)19.25(14.09-32.85)33.07(12.41-178.52)11.26(7.08-26.45)5.50(3.00-13.05)
 P valueP=0.001P<0.001P<0.001P<0.001P<0.001
Group by UACR
 UACR≤30(mg/gCr)3341.29(0.50-3.19)8.15(4.81-13.57)9.07(5.61-14.56)4.79(3.22-7.10)2.40(1.60-3.70)
 UACR>30(mg/gCr)1861.32(0.54-3.30)18.54(10.35-35.86)103.47(52.24-399.14)16.68(9.17-45.42)6.65(3.88-21.53)
 P valueP=0.566P<0.001P<0.001P<0.001P<0.001
Group by UIGG
 UIGG ≤5(mg/gCr)1901.10(0.49-2.70)5.26(3.92-8.37)7.52(4.53-11.75)3.40(2.66-4.13)1.90(1.40-2.50)
 UIGG >5(mg/gCr)3301.38(0.55-3.82)15.22(9.13-28.10)33.47(12.05-133.04)10.09(6.95-20.53)4.95(3.40-10.23)
 P valueP=0.052P<0.001P<0.001P<0.001P<0.001
Group by UTRF
 UTRF ≤1.5(mg/gCr)811.10(0.50-2.42)4.30(2.89-8.22)7.07(4.39-11.66)2.66(2.09-3.67)1.20(1.00-1.40)
 UTRF >1.5(mg/gCr)4391.30(0.52-3.40)12.41(7.10-22.94)21.70(8.70-74.76)7.68(4.77-15.37)3.80(2.50-7.10)
 P valueP=0.268P<0.001P<0.001P<0.001P<0.001

Data are shown as median (IQR)
hsCRP: hypersensitive C-reactive protein; UA1MG: Urinary alpha1-microglobulin to creatinine ratio; UACR: Urinary microalbumin to creatinine ratio; UIGG: Urinary immunoglobulin G to creatinine ratio; UTRF: Urinary transferrin to creatinine ratio.