Fungal Keratitis: Epidemiology, Rapid Detection, and Antifungal Susceptibilities of Fusarium and Aspergillus Isolates from Corneal Scrapings

Table 2

Minimum inhibitory concentration (μg/ml) of antifungal agents against Fusarium spp. (n=200).

Amphotericin B
MIC range	≤0.5 μg/ml	≥1 μg/ml	MIC50	MIC90
8 – 0.125	77 (38.5%)	123 (61.5%)	1	1
Natamycin
MIC range	≤8 μg/ml	≥16 μg/ml	MIC50	MIC90
64 – 2	70 (35%)	130 (65%)	16	32
Itraconazole
MIC range	≤16 μg/ml	≥32 μg/ml	MIC50	MIC90
32 – 4	15 (7.5%)	185 (92.5%)	32	32
Voriconazole
MIC range	≤4 μg/ml	≥8 μg/ml	MIC50	MIC90
8 – 1	101 (50.5%)	99 (49.5%)	4	8
Econazole
MIC range	≤4 μg/ml	≥8 μg/ml	MIC50	MIC90
8 – 2	38 (19%)	162 (81%)	8	8
Clotrimazole
MIC range	≤4 μg/ml	≥8 μg/ml	MIC50	MIC90
8 – 0.5	145 (72.5%)	55 (27.5%)	4	8
Ketoconazole
MIC range	≤8 μg/ml	≥16 μg/ml	MIC50	MIC90
16 – 2	35 (17.5%)	165 (82.5%)	16	16