Single Nucleotide Polymorphisms of CBX4 and CBX7 Decrease the Risk of Hepatocellular Carcinoma
Table 5
Results of SNP-SNP interaction analyses.
Factors
SE (βi)
OR (95% CI)
P-value
rs2289728× rs7217395
0.60
0.51
1.82 (0.67-4.99)
0.24
rs2289728× rs2036316
0.50
0.56
1.66 (0.55-4.95)
0.37
rs2289728× rs3764374
-0.04
0.54
0. 96 (0.33-2.79)
0.95
rs2289728× rs1285251
-0.735
0.57
0. 48 (0.16-1.46)
0.20
rs2289728×rs7292074
0.28
0.52
1.33 (0.48-3.68)
0.59
rs2289728×rs710190
0.51
0.52
1.66 (0.61-4.56)
0.33
rs2289728×rs139394
-0.57
0.52
0.57 (0.21-1.56)
0.27
rs2289728×rs5750753
0.71
0.57
2.04 (0.67-6.18)
0.21
rs139394× rs7217395
-0.30
0.48
0. 74 (0.29-1.91)
0.54
rs139394× rs2036316
0.28
0.53
1.327 (0.47-3.68)
0.60
rs139394× rs3764374
0.18
0.49
1.20 (0.46-3.12)
0.71
rs139394× rs1285251
0.69
0.48
2.00 (0.79-5.09)
0.15
rs139394× rs7292074
-0.07
0.49
0.93 (0.36-2.42)
0.89
rs139394× rs710190
-1.12
0.53
0.33 (0.12-0.91)
0.03
rs139394×rs5750753
-0.27
0.63
0.77 (0.22-2.62)
0.67
Bold values indicate statistical significance. a: adjusted age, gender, smoking habits, alcohol intake, and HBsAg values by logistic regression and the independent effect of each SNP. Values of these covariates in logistic regression models were shown in Table S3.
