BioMed Research International / 2019 / Article / Tab 4

Research Article

Inhibition of the Nrf2-TrxR Axis Sensitizes the Drug-Resistant Chronic Myelogenous Leukemia Cell Line K562/G01 to Imatinib Treatments

Table 4

The impacts of siRNA-mediated Nrf2 knockdown to the mRNA expressions of Nrf2 and TrxR in K562/G01 cells.

GeneGroupΔCT ()RQ ()

Nrf2K562/G013.15 ± 0.300.98 ± 0.21
NC-GFP-LV3.23 ± 0.900.98 ± 0.44
Nrf2-RNAi-LV4.63 ± 0.290.33 ± 0.09

TrxRK562/G0119.22 ± 0.251.01 ± 0.17
NC-GFP-LV18.97 ± 0.680.92 ± 0.44
Nrf2-RNAi-LV20.50 ± 0.310.42 ± 0.13

, compared with the uninfected K562/G01 group or NC-GFP-LV-infected group; n = 3 for each group.