Intra-Arrest Administration of Cyclosporine and Methylprednisolone Does Not Reduce Postarrest Myocardial Dysfunction
Table 1
Baseline Characteristics.
CCY + MP (n = 5)
Control (n = 6)
Hemodynamics
MAP (mmHg)
88 (88-96)
85 (74-92)
CO (L/min)
2.8 (1.9-3.1)
2.7 (2.1-3.9)
Arrest characteristics
Weight (kg)
25.0 (24.4-27.5)
24.2 (23.8-25.4)
CPR duration (min)
7 (5-7)
7 (5-13)
Countershocks (#)
2 (1.5-2)
2 (1-5)
Epinephrine bolus (#)
2
2 (1-3)
Laboratory values
pH
7.56 (7.54-7.58)
7.55 (7.49-7.60)
pCO2 (mmHg)
38 (37-40)
32 (31-38)
pO2 (mmHg)
89 (88-240)
93 (77-107)
HCO3 (meq/L)
33.9 (33.7-37.1)
29.8 (29.6-32.4)
Sp02 (%)
98 (98-100)
99 (96-99)
Na (meq/L)
140 (140-142)
142 (141-142)
K (meq/L)
3.5 (3.1-3.7)
3.4 (3.2-3.7)
Ca (meq/L)
1.35 (1.28-1.39)
1.22 (1.17-1.34)
Glu (mmol/L)
119 (110-125)
102 (96-111)
Hct
25 (25-27)
25 (24-26)
Echocardiographic parameters
LVEDD (cm)
3.5 (3.3-3.6)
2.9 (2.9-3.0)
LVESD (cm)
2.7 (2.4-2.9)
2.1 (2.0-2.2)
Fractional Shortening (%)
23.9 (19.3-28.5)
26.9 (24.3-32.8)
LVEF (%)
35.6 (29.0-42.3)
37.5 (328.0-42.6)
Data is shown as median (IQR). CO, cardiac output; Glu, glucose; Hct, Hematocrit; LVEDD, left ventricular end diastolic diameter; LVEF, left ventricular ejection fraction; LVESD, left ventricular end systolic diameter; MAP, mean arterial pressure; ROSC, return of spontaneous circulation
