Brucine Suppresses Vasculogenic Mimicry in Human Triple-Negative Breast Cancer Cell Line MDA-MB-231

Figure 3

The aberrations of F-actin cytoskeleton and microtubule structure induced by brucine. After MDA-MB-231 cells treated with brucine (0.5; 1 mM) for 24 h, the disruption of F-actin cytoskeleton stained by Alexa Fluor™ 488 Phalloidin (a) and microtubule structure indicated by immunofluorescence staining (b) were observed under a confocal laser-scanning microscopy. Nuclei were counterstained with DAPI (blue). The scale bar is of 5 μm.

(a)

(b)