Anti-Shigellosis Activity of Cola anomala Water/Ethanol Pods Extract on Shigella flexneri-Induced Diarrhea in Rats

Table 3

Blood cell count in Shigella flexneri-infected rats after treatment with C. anomala water/ethanol extract and ciprofloxacin.

	DC	NC	CIP	KEO25	KEO50	KEO100
WBC × 10^9/L	6.40 ± 0.20	4.20 ± 0.20^b1	5.00 ± 0.50	6.60 ± 0.50^b	4.80 ± 0.30	5.20 ± 0.30
RBC × 10^12/L	6.62 ± 0.39	6.03 ± 0.32	6.57 ± 0.20	6.45 ± 0.49	6.34 ± 0.33	6.28 ± 0.25
Hb (g/dL)	12.90 ± 0.60	12.00 ± 0.50	13.00 ± 0.20	12.80 ± 0.50	12.80 ± 0.30	12.70 ± 0.20
HCT (%)	39.90 ± 2.10	36.10 ± 1.60	38.10 ± 1.50	37.80 ± 2.70	35.80 ± 1.30	35.60 ± 1.30
Pc × 10^9/L	685.20 ± 45.70	760.80 ± 42.20	742.40 ± 20.60	708.00 ± 47.40	687.40 ± 28.80	702.20 ± 44.60
MGV (fL)	57.50 ± 1.50	59.40 ± 0.70	57.40 ± 0.60	57.00 ± 0.70	55.70 ± 1.10	57.20 ± 0.30
MGH (ρg)	18.70 ± 1.10	21.20 ± 0.80	20.70 ± 0.70	19.80 ± 1.00	18.20 ± 1.00	20.10 ± 1.00
MCHC (g/dL)	35.10 ± 1.00	31.80 ± 1.40	35.00 ± 1.40	34.00 ± 1.40	32.70 ± 1.20	34.20 ± 1.70

KEO25, KEO50, and KEO100: C. anomala water/ethanol extract at 25, 50, and 100 mg/kg; CIP: ciprofloxacin 2.5 mg/kg; NC: normal control; DC: diarrheic control; WBC: white blood cell; Hb: haemoglobin; HTC: hematocrit; RBC: red blood cell; Pc: platelets; MGV: mean globular volume; MGH: mean globular haemoglobin; MCHC: mean corpuscular haemoglobin concentration (n = 5). Significant difference: b1: , compared to diarrheic control (DC); b: , compared to normal control (NC).