Diuretic and Antidiuretic Activities of Ethanol Extract and Fractions of Lagopsis supina in Normal Rats

Table 1

Effects of LS, LSA, LSB, LSC, and LSD on urinary excretion volume (mL) within 1, 2, 4, 6, and 24 h after oral administration.

Group	1 h	2 h	4 h	6 h	24 h
Control	2.07 ± 0.64	4.45 ± 1.28	6.77 ± 1.23	9.13 ± 1.25	17.73 ± 0.80
Furosemide	7.15 ± 2.00	11.45 ± 1.69	14.02 ± 2.11	16.85 ± 1.89	34.68 ± 3.51
LS-H	2.37 ± 1.00	4.53 ± 2.08	6.58 ± 2.22	9.72 ± 2.28	28.27 ± 3.89
LS-M	3.28 ± 1.64	6.22 ± 1.97	8.87 ± 1.65	10.63 ± 1.79	25.30 ± 2.71
LS-L	2.98 ± 1.05	6.52 ± 1.63	8.18 ± 1.60	9.43 ± 1.56	17.17 ± 1.95
LSA-H	3.50 ± 1.47	6.27 ± 2.21	8.27 ± 2.08	10.53 ± 2.30	24.68 ± 2.50
LSA-L	3.98 ± 0.89	5.80 ± 1.45	7.37 ± 1.75	9.45 ± 1.98	19.75 ± 2.07
LSB-H	2.78 ± 1.36	5.30 ± 1.38	7.82 ± 1.60	10.98 ± 2.08	38.18 ± 3.45
LSB-L	3.12 ± 0.99	5.18 ± 1.37	6.63 ± 1.76	8.68 ± 1.02	15.13 ± 1.97
LSC-H	2.00 ± 0.93	5.00 ± 1.74	6.14 ± 2.01	8.10 ± 1.07	24.62 ± 3.07
LSC-L	2.98 ± 0.81	5.52 ± 0.96	7.83 ± 1.97	12.27 ± 1.41	27.25 ± 3.00
LSD-H	2.25 ± 1.00	3.77 ± 1.23	5.10 ± 1.11	7.33 ± 1.81	20.73 ± 2.80
LSD-L	1.19 ± 0.61	4.08 ± 0.90	6.58 ± 1.41	9.23 ± 1.74	21.02 ± 2.38

The cumulative values are reported as mean ± SD for 8 rats in each group. and compared to the control.