Diuretic and Antidiuretic Activities of Ethanol Extract and Fractions of Lagopsis supina in Normal Rats

Table 4

Effects of LS, LSA, LSB, LSC, and LSD on urinary electrolyte K⁺ (mmol/L) concentrations within 1, 2, 4, 6, and 24 h after oral administration.

Group	1 h	2 h	4 h	6 h	24 h
Control	78.98 ± 5.35	79.40 ± 5.53	79.38 ± 5.41	78.83 ± 5.08	79.03 ± 5.38
Furosemide	150.85 ± 26.84	148.80 ± 24.93	122.00 ± 10.53	95.20 ± 1.40	61.55 ± 10.50
LS-H	97.80 ± 2.37	96.88 ± 2.29	95.35 ± 2.03	94.85 ± 2.33	94.48 ± 2.92
LS-M	93.83 ± 6.13	91.28 ± 5.01	85.73 ± 4.81	84.00 ± 5.36	85.38 ± 4.60
LS-L	86.80 ± 6.34	85.45 ± 6.12	85.43 ± 3.75	84.00 ± 3.41	74.88 ± 6.97
LSA-H	62.18 ± 3.20	58.20 ± 3.40	57.30 ± 2.08	61.25 ± 0.94	77.50 ± 5.12
LSA-L	76.28 ± 7.20	75.83 ± 6.19	77.58 ± 4.64	77.75 ± 4.48	76.75 ± 2.86
LSB-H	79.75 ± 2.41	81.08 ± 1.86	81.98 ± 2.75	82.20 ± 2.82	90.28 ± 5.46
LSB-L	65.50 ± 11.12	68.33 ± 7.23	68.58 ± 7.01	68.83 ± 7.47	71.58 ± 8.31
LSC-H	70.43 ± 3.19	69.53 ± 2.28	69.63 ± 1.79	67.68 ± 2.34	58.78 ± 5.93
LSC-L	82.15 ± 10.62	81.33 ± 10.07	79.80 ± 9.77	74.53 ± 8.26	75.80 ± 10.62
LSD-H	65.25 ± 5.55	63.38 ± 5.58	61.85 ± 4.26	60.58 ± 4.03	52.13 ± 6.36
LSD-L	85.78 ± 3.46	83.23 ± 2.10	81.28 ± 2.99	80.48 ± 1.50	78.30 ± 1.26

The values are reported as mean ± SD for 8 rats in each group. and compared to the control.