Research Article

Diuretic and Antidiuretic Activities of Ethanol Extract and Fractions of Lagopsis supina in Normal Rats

Table 8

Effects of LS, LSA, LSB, LSC, and LSD on TNF-α and IL-6 levels in urine and serum of rats within 24 hours after administration.

GroupUrineSerum
TNF-αIL-6TNF-αIL-6

Control145.23 ± 22.5282.98 ± 13.99143.26 ± 28.0672.33 ± 14.42
Furosemide143.63 ± 27.5772.49 ± 13.88157.04 ± 18.1973.00 ± 13.80
LS-H124.22 ± 13.8174.28 ± 15.85132.04 ± 29.9865.00 ± 16.58
LS-M133.71 ± 10.6571.04 ± 15.41139.90 ± 26.8968.20 ± 13.81
LS-L140.29 ± 12.8178.68 ± 16.32144.14 ± 14.8269.83 ± 16.67
LSA-H129.00 ± 16.0472.29 ± 11.08135.28 ± 30.5874.12 ± 12.77
LSA-L150.42 ± 21.7766.29 ± 13.32125.14 ± 12.8170.25 ± 11.50
LSB-H142.03 ± 15.0478.49 ± 13.28152.62 ± 28.0469.88 ± 13.63
LSB-L133.51 ± 10.8069.42 ± 13.98139.21 ± 31.2771.76 ± 16.86
LSC-H131.41 ± 21.7069.89 ± 12.69146.63 ± 24.6462.38 ± 11.05
LSC-L130.78 ± 19.4361.23 ± 12.00150.14 ± 14.1873.59 ± 12.98
LSD-H146.98 ± 23.3171.45 ± 6.88139.26 ± 21.2873.82 ± 19.00
LSD-L140.21 ± 19.6281.43 ± 14.91134.78 ± 32.0175.81 ± 15.07

The values are reported as mean ± SD for 8 rats in each group.