Nav1.7 via Promotion of ERK in the Trigeminal Ganglion Plays an Important Role in the Induction of Pulpitis Inflammatory Pain

Figure 7

Western blotting analysis of ERK expression in the TG of control and pulp-exposed rats. The Nav1.7 in TG from the sham, pulpitis rats, and rats with pulpitis given PF04856264 (an Nav1.7 antagonist, 30 mg/kg) in the same blot on postoperative day 14. Representative gel images and summary data show that the intensity of ERK is increased in pulpitis rats compared with that in the sham rats.