Therapeutic Effect of Dunaliella salina Microalgae on Thioacetamide- (TAA-) Induced Hepatic Liver Fibrosis in Rats: Role of TGF-β and MMP9
Table 1
Effects of D. salina powder on serum hepatic function biomarkers.
Normal control
TAA
Silymarin (100 mg/kg)
D. salina powder (100 mg/kg)
D. salina powder (200 mg/kg)
ALT (U/L)
43.14 ± 0.18
68.52 ± 0.62a
47.95 ± 0.05b
53.70 ± 0.04ab
48.64 ± 0.12b
% of TAA control
70
78
71
AST (U/L)
56.48 ± 0.04
89.01 ± 0.26a
68.56 ± 0.37ab
72.78 ± 0.15ab
69.28 ± 0.03ab
% of TAA control
77
82
78
Bilirubin (mg/dl)
1.44 ± 0.11
1.89 ± 0.01a
1.56 ± 0.06b
1.62 ± 0.06
1.55 ± 0.07b
% of TAA control
83
86
82
Albumin (g/dl)
4.13 ± 0.03
3.56 ± 0.14a
3.90 ± 0.05b
3.59 ± 0.00a
3.91 ± 0.01b
% of TAA control
110
101
110
Data are presented as mean ± SE for each group (n = 8) and % of the TAA group. Statistical analysis was carried out by one-way analysis of variance followed by Tukey’s multiple comparisons test. aStatistically significant from the control group. bStatistically significant from the TAA group at .