Therapeutic Effect of Dunaliella salina Microalgae on Thioacetamide- (TAA-) Induced Hepatic Liver Fibrosis in Rats: Role of TGF-β and MMP9

Table 1

Effects of D. salina powder on serum hepatic function biomarkers.

	Normal control	TAA	Silymarin (100 mg/kg)	D. salina powder (100 mg/kg)	D. salina powder (200 mg/kg)
ALT (U/L)	43.14 ± 0.18	68.52 ± 0.62^a	47.95 ± 0.05^b	53.70 ± 0.04^ab	48.64 ± 0.12^b
% of TAA control			70	78	71
AST (U/L)	56.48 ± 0.04	89.01 ± 0.26^a	68.56 ± 0.37^ab	72.78 ± 0.15^ab	69.28 ± 0.03^ab
% of TAA control			77	82	78
Bilirubin (mg/dl)	1.44 ± 0.11	1.89 ± 0.01^a	1.56 ± 0.06^b	1.62 ± 0.06	1.55 ± 0.07^b
% of TAA control			83	86	82
Albumin (g/dl)	4.13 ± 0.03	3.56 ± 0.14^a	3.90 ± 0.05^b	3.59 ± 0.00^a	3.91 ± 0.01^b
% of TAA control			110	101	110

Data are presented as mean ± SE for each group (n = 8) and % of the TAA group. Statistical analysis was carried out by one-way analysis of variance followed by Tukey’s multiple comparisons test. ^aStatistically significant from the control group. ^bStatistically significant from the TAA group at .