Gingko biloba Extract (EGb) Inhibits Oxidative Stress in Neuro 2A Cells Overexpressing APPsw

Figure 5

Effects of EGb on antioxidant enzyme activities in N2a, N2a-APP695, and N2a-APPsw cells. Compared with N2a cells, the activity of T-SOD (a), CAT (b), and GSH-Px (c) in N2a-APP695 and N2a-APPsw cells was significantly decreased. However, after treatment with 100 μg/ml EGb for 8 h, the activities of the antioxidant enzymes were significantly increased in the cell homogenates from N2a-APP695 and N2a-APPsw. All values are presented as the mean ± SD from three independent experiments. p <0.05, p <0.01, and p <0.001.

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