BioMed Research International / 2019 / Article / Tab 2

Research Article

Functional Variant rs4442975 Modulating FOXA1 Binding Affinity Can Influence Bone Marrow Suppression during Neoadjuvant Chemotherapy for Luminal A Type Breast Cancer

Table 2

Association between rs4442975 and the efficacy of NAC.

VariableEfficacy
Effective (pCR + CR + PR)Invalid (SD + PD) (95% CI); P
N (%)N (%)

rs444297514026
TT101 (72.14)20 (76.92)1.00
GT37 (26.43)6 (23.08)0.76 (0.28–2.07); 0.588
GG2 (1.43)0
Dominant0.74 (0.27–2.01); 0.556
Additive0.73 (0.27–1.94); 0.527

ratios (ORs) and 95% confidence intervals (CIs) were calculated using unconditional logistic regression analysis after adjusting for age, smoking, alcohol use, and menopausal status.