Functional Variant rs4442975 Modulating FOXA1 Binding Affinity Can Influence Bone Marrow Suppression during Neoadjuvant Chemotherapy for Luminal A Type Breast Cancer

Table 2

Association between rs4442975 and the efficacy of NAC.

Variable	Efficacy
	Effective (pCR + CR + PR)	Invalid (SD + PD)	(95% CI); P
	N (%)	N (%)
rs4442975	140	26
TT	101 (72.14)	20 (76.92)	1.00
GT	37 (26.43)	6 (23.08)	0.76 (0.28–2.07); 0.588
GG	2 (1.43)	0	–
Dominant			0.74 (0.27–2.01); 0.556
Additive			0.73 (0.27–1.94); 0.527

ratios (ORs) and 95% confidence intervals (CIs) were calculated using unconditional logistic regression analysis after adjusting for age, smoking, alcohol use, and menopausal status.