The Effect of Butyrate-Supplemented Parenteral Nutrition on Intestinal Defence Mechanisms and the Parenteral Nutrition-Induced Shift in the Gut Microbiota in the Rat Model

Figure 4

The effect of butyrate on tight junction proteins mRNA expression and intestinal permeability. (a) ZO-1 mRNA; (b) E-cadherin mRNA; (c) claudin-7 mRNA; (d) HRP leakage in vitro. mRNA expression is given as a fold change over the control group. Results are presented using Tukey box-and-whisker plots as quartiles (25%, median, and 75%). p<0.05 PN versus control; ^††p<0.01 PN+But versus control; ^#p<0.05; ^##p<0.01 PN+But versus PN.

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