Review Article

The Diagnostic Performance of Afirma Gene Expression Classifier for the Indeterminate Thyroid Nodules: A Meta-Analysis

Table 6

Pooled sensitivities: confidence interval and heterogeneity results.

ā€‰Estimate95% CII2QP

Se0.955(0.935, 0.970)65.00%42.87<0.001
Sp0.221(0.194, 0.249)89.10%137.13<0.001
PLR1.167(1.088, 1.252)77.50%66.74<0.001
NLR0.285(0.199, 0.410)0.00%10.630.778
DOR5.248(3.425, 8.043)0.00%9.420.855

Se, sensitivity; Sp, specificity; PLR, positive likelihood ratio; NLR, negative likelihood ratio; DOR, diagnostic odds ratio; I2, inconsistency I-square; Q, Chi-square.