Research Article

Long Noncoding RNAs and Messenger RNAs Expression Profiles Potentially Regulated by ZBTB7A in Nasopharyngeal Carcinoma

Figure 1

RNA expression profiles in shRNA-CNE2 and NC-CNE2 cells. Hierarchical clustering indicated (a) lncRNA and (b) mRNA profiles. Box plot of (c) lncRNA or (d) mRNA profiles was a traditional method for visualizing separately the distribution of dataset. Scatter plot of (e) lncRNA or (f) mRNA profiles was a convenient visualization for assessing the variation of chips. T1-T3 meant test groups which were stably transfected with shRNA plasmid targeting ZBTB7A. C1-C3 meant negative control groups which were stably transfected with blank plasmid. ‘Red’ showed relatively high expression. ‘Green’ showed relatively low expression. The values of the x- and y-axes were the average normalized signal values of NC-CNE2 and shRNA-CNE2 in the scatter plot ( scaled).

(a)
(b)
(c)
(d)
(e)
(f)