Long Noncoding RNAs and Messenger RNAs Expression Profiles Potentially Regulated by ZBTB7A in Nasopharyngeal Carcinoma
Figure 4
The differentially expressed mRNAs in important ranked pathways. (a) Upregulated mRNAs in steroid hormone biosynthesis. 2.8.2.2, SULT2B1 (sulfotransferase family 2B member 1); 1.3.1.22, SRD5A3 (steroid 5 alpha-reductase 3); 1.1.1.213, AKR1C2 (aldo-keto reductase family 1 member C2); 1.1.1.50, AKR1C4; 1.1.1.149, AKR1C1; 1.1.1.51, AKR1C3; 1.14.14.1, CYP3A5 (cytochrome P450 family 3 subfamily A member 5); 1.14.13.-, CYP3A4 (cytochrome P450 family 3 subfamily A member 4); 2.4.1.17, UGT1A6, (UDP glucuronosyltransferase family 1 member A6). (b) Downregulated mRNAs in PPAR signaling pathway. PPAR, peroxisome proliferators-activated receptor; FABP, fatty acid binding protein; aP2, FABP4; HMGCS2, 3-hydroxy-3-methylglutaryl-CoA synthase 2; Apo-CIII, apolipoprotein C3; MCAD, ACADM (acyl-CoA dehydrogenase medium chain); GyK, GK (glycerol kinase). The regulated mRNAs in shRNA-CNE2 compared to NC-CNE2 were marked in coloured boxes. Red box indicated an upregulated mRNA; yellow box indicated a downregulated mRNA; green box indicated that no significant difference was observed.