Research Article

Long Noncoding RNAs and Messenger RNAs Expression Profiles Potentially Regulated by ZBTB7A in Nasopharyngeal Carcinoma

Table 3

Top up-regulated and down-regulated KEGG pathways of carbohydrate and lipid metabolisms (shRNA-CNE2 vs. NC-CNE2, p<0.05).

Pathway IDDefinitionCountEnrichment Fisher-P
ScoreValue

Up-regulated
 hsa00140Steroid hormone biosynthesis585.043010.00000906
 hsa00100Steroid biosynthesis463.1298420.00074158
 hsa05205Proteoglycans in cancer2041.9703210.01070727
 hsa00053Ascorbate and aldarate metabolism271.7448020.01799693
Down-regulated
 hsa03320PPAR signaling pathway692.0354160.00921689
 hsa00072Synthesis and degradation of101.5704790.02688568
ketone bodies
 hsa00510N-Glycan biosynthesis491.408860.03900677