Dihydrochalcone Derivative Induces Breast Cancer Cell Apoptosis via Intrinsic, Extrinsic, and ER Stress Pathways but Abolishes EGFR/MAPK Pathway

<div>Chemical structures of dihydrochalcone derivatives used in the study. Compound 1 (4′,6′-dihydroxy-2′,4-dimethoxy-5'-(2″-hydroxybenzyl)dihydrochalcone) (a) and compound 2 (calomelanone; 2′,6′-dihydroxy-4,4′-dimethoxydihydrochalcone) (b).</div>

BioMed Research International

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Figure 1

Figure 1: Dihydrochalcone Derivative Induces Breast Cancer Cell Apoptosis via Intrinsic, Extrinsic, and ER Stress Pathways but Abolishes EGFR/MAPK Pathway 

Figure 1 | Dihydrochalcone Derivative Induces Breast Cancer Cell Apoptosis via Intrinsic, Extrinsic, and ER Stress Pathways but Abolishes EGFR/MAPK Pathway 