Dihydrochalcone Derivative Induces Breast Cancer Cell Apoptosis via Intrinsic, Extrinsic, and ER Stress Pathways but Abolishes EGFR/MAPK Pathway

Table 2

Inhibitory concentrations of compound 1 at 24 hours.

Cell types	Concentrations of compound 1 (μM)
	IC10	IC20	IC50
MDA-MB-231	57.1 ± 3.5	84.8 ± 2.8	232.7 ± 3.9
MCF-7	22.8 ± 3.7	45.7 ± 4.8	88.3 ± 5.4
NIH3T3	—	—	>200
PBMCs	—	—	>200

, IC₅₀ of compound 1-treated MDA-MB-231 compared with compound 1-treated MCF-7 at 24 hours.