The Influence of FTO Polymorphism rs9939609 on Obesity, Some Clinical Features, and Disturbance of Carbohydrate Metabolism in Patients with Psoriasis

Table 2

Clinical characteristics and carbohydrate parameters (mean ± SD) of PSO-patients according to AA, AA+AT and TT genotypes.

Parameter	Carriers of AA genotype; n=41	Carriers of AA+AT genotype; n=123	Carriers of TT genotype; n=74	P	P
Age (years)	49.8±15.9	51.01±14.07	49.36±14.19	0.56	0.42
BMI (kg/m^2)	28.6±6.5	29.52±7.05	26.25±5.55	0.002	0.0005
Waist (cm)	100.87±14.76	101.71±16.07	96.34±14.28	0.14	0.05
Hip (cm)	104.96±8.63	105.69±10.72	101.00±9.72	0.02	0.06
WHR	0.95±0.09	0.96±0.09	0.95±0.09	0.82	0.53
(mm Hg)	137.70±20.20	135.85±20.79	133.83±24.18	0.32	0.33
(mm Hg)	83.65±11.07	83.87±11.17	83.01±13.39	0.62	0.63
PASI	11.96 ±6.38	10.62±7.75	10.01±8.55	0.02	0.10
CRP (mg/dl)	14.39±26.93	11.22±20.26	7.77±16.58	0.07	0.04
ESR (mm/h)	26.00±22.24	22.95±20.17	19.34±17.69	0.09	0.14
Glucose (mg/dl)	95.60±42.45	92.10±30.46	87.14±15.62	0.97	0.85
Insulin (µIU/ml)	9.64±6.10	12.32±13.31	8.78±7.28	0.34	0.05
HOMA	2.46±3.62	2.96±3.93	1.90±1.50	0.52	0.07
FIRI	1.51±3.26	2.66±3.53	1.71±1.35	0.52	0.07
QUCIKI	0.36±0.06	0.35±0.05	0.36±0.05	0.52	0.07

value - AA vs. TT
value - AA + AT vs. TT