Relationships of SLC2A4, RBP4, PCK1, and PI3K Gene Polymorphisms with Gestational Diabetes Mellitus in a Chinese Population

Table 2

Demographic and clinical characteristics of the study subjects.

	Controls (N=367)	Cases (N=334)	p
Maternal age, years	29(28,32)	29(27,32)	0.672
Gestational age at sampling, weeks	25.11±2.724	25.35±2.948	0.458
Pre-pregnancy BMI	20.55(19.14,22.64)	22.31(20.29,24.14)	<0.001
Weekly BMI growth	0.114±0.054	0.131±0.056	<0.001
SBP	111±10.30	116±11.12	<0.001
DBP	70±8.38	74±8.09	<0.001
Parity
0	230(62.7%)	216(64.7%)	0.312
1	123(33.5%)	93(27.8%)
2	5(1.4%)	7(2.1%)
Family history of diabetes
Yes	62(17.4%)	94(29.3%)	<0.001
No	295(82.6%)	227(70.7%)

The Wilcoxon rank sum test was used due to a nonnormal distribution of the tested characteristics, and data are presented as medians and quartiles. Student’s t-test was used due to a normal distribution of the tested characteristics, and data are presented as the mean and SDs. A Chi-square test was used to analyse data presented as a ratio. BMI measured on the morning of the oral glucose tolerance test minus the prepregnancy BMI and then divided by the gestational age (weeks) was defined as “Weekly BMI growth”; SBP (systolic blood pressure) and DBP (diastolic blood pressure) were the blood pressures measured on the morning of the oral glucose tolerance test. Relatives covered grandfather, grandmother, maternal grandfather, maternal grandmother, father, mother, brother, sister, and brother and sister of father and mother.