NOCTURNIN Gene Diurnal Variation in Healthy Volunteers and Expression Levels in Shift Workers

Figure 1

NOCTURNIN expression profiles calculated in lymphocytes from 15 healthy volunteers collected at 4-hour intervals over 24 h. NOCTURNIN mRNA levels are expressed as geometric mean ± 95% confidence interval. A significant diurnal variation was highlighted by repeated measures ANOVA and Cosinor analysis. p < 0.05 compared to nearest times.