Antimicrobial and Antibiofilm Activity against Streptococcus mutans of Individual and Mixtures of the Main Polyphenolic Compounds Found in Chilean Propolis

Table 3

Antimicrobial activity of individual compounds and polyphenols mixture on S. mutans cultures.

Compounds	MIC	p-value vs Quercetin	p-value vs CAPE
Polyphenols Mixture	1.6 ± 0.4	p<0.5	p<0.001
Apigenin	1.3 ± 0.4	p<0.01	p<0.001
Pinocembrin	1.4 ± 0.4	p<0.01	p<0.001
Chlorhexidine	1.6 ± 0.2	p<0.5	p<0.001
Quercetin	4.1 ± 0.8	-	NSD
CAPE	5.2 ± 0.8	NSD	-

MIC: minimum inhibitory Concentration. MIC values were expressed in μg mL⁻¹ as Mean ± Standard Deviation. P-value was calculated as significant differences after ANOVA Multiple Comparison and test Tukey’s Posttest. NSD: Nonstatistical Differences.