Research Article

Relationship of Natriuretic Peptides with Left Atrial Structure and Function within 1 Month after Electrical Cardioversion in Patients with Persistent Atrial Fibrillation

Table 1

Patients’ baseline characteristics according to rhythm status after 1 month.

Total (n= 48)SR group (n = 26)AF group (n= 22)p value

Age, years65.15±10.1964.04±9.6666.45±10.880.424
Sex, males33 (67.3%)18 (69.2%)14 (63.6%)0.480
AF history
<1 year26 (53.1%)15 (57.7%)11 (50.0%)0.433
1-3 years8 (16.3%)4 (15.4%)4 (18.2%)
>3 years14 (28.6%)7 (26.9%)7 (31.8%)
AF duration before ECV
<3 months27 (55.1%)17 (65.4%)10 (45.5%)0.178
3-6 months13 (26.4%)5 (19.2%)8 (36.4%)0.405
6-12 months8 (16.3%)4 (15.4%)4 (18.2%)
Hypertension42 (85.7%)22 (84.6%)20 (90.9%)0.758
Diabetes5 (10.2%)5 (19.2%)0

Echocardiographic parameters within the first 24 hours after SR restoration
Left ventricular ejection fraction, %53.76±11.8252.84±13.4654.78±9.990.67
Left ventricular end diastolic diameter, mm50.72±4.1551.29±3.4950.07±4.810.28
LA diameter, mm48.66±4.2648.21±4.0949.17±4.520.61
LA volume, ml/m251.85 (45.34-57.78)49.94 (39.89-57.09)52.10 (47.94-61.71)0.19
LA reservoir function, %24.16 (19.99-33.21)24.79 (18.56-35.16)24.12 (24.12-32.95)0.85
LA conduit function, %15.88±6.3316.51±7.4815.94±5.680.67
LA pump function, %9.67 (6.97-14.88)8.47 (6.27-15.02)10.34 (7.63-13.74)0.54

Medications
Propafenone10 (20.4%)2 (7.4%)8 (36.4%)0.06
Amiodarone19 (38.8%)16 (59.3%)3 (13.6%)0.003
β-blocker45 (91.8%)24 (88.9%)21 (95.5%)0.66
ACEI or ARB37 (75.5%)20 (74.1%)17 (77.3%)0.62
Statins10 (20.4%)6 (22.2%)4 (18.2%)0.53

Plasma levels of natriuretic peptides
NT-proBNP, ng/L1763.50 (1030.25-2556.00)2276.00 (918.00-3186.00)1670.00 (1119.00-2280.25)0.96
NT-proANP, ng/L51181.00 (39243.00-82423.00)55626.00 (41052.75-83724.75)48133.00 (33972.50-73533.00)0.31