Identification of Potential Biomarkers and Biological Pathways in Juvenile Dermatomyositis Based on miRNA-mRNA Network

Table 5

Differentially expressed miRNAs in autoimmune diseases.

Autoimmune diseases	Differentially expressed miRNAs		References
	Upregulation	Downregulation
Juvenile dermatomyositis	miR-193b, miR-199b-5p	miR-665	—
Multiple sclerosis	miR-186, miR-145, miR-125a-5p, miR-331-3p, miR-146a, miR-362-5p, miR-501-5p, miR-491-5p, miR-142-3p, miR-29b, miR-328, miR-92b, miR-30a, let-7b, miR-425, miR-520a-3p, miR-596, miR-378, miR-29c, miR-20b	miR-20a, miR-211, miR-374a, miR-107, miR-633, miR-93, miR-410, miR-196a, hsa-miR-582-5p, miR-579, miR-1251, miR-363, miR-572, miR-519e, miR-32, miR-15b, miR-580, miR-556-5p, miR-510, miR-663, miR-638, miR-369-3p, miR-208b, miR-200a, miR-126	[17, 18]
Type 1 diabetes	miR-375, miR-152, miR-30a-5p, miR-181a, miR-24, miR-148a, miR-210, miR-27a, miR-29a, miR-26a, miR-27b, miR-25, and miR-200a,	miR-21a and miR-93	[19, 20]
Primary biliary cirrhosis	miR-299-5p, miR-328, miR-371	miR-26a, miR-122a, miR-99a	[21]
Graves’ disease	miR-17, miR-155, miR-200a1	miR-146a	[22]
Ulcerative colitis	miR-16, miR-21, miR-23a, miR-24, miR-29a, miR-126, miR-195, and Let-7f	miR-192, miR-375, and miR-422b	[23]
Coeliac disease	miR-182, miR-196a, miR-330, miR-449a, miR-492, miR-500, miR-503, miR-504, miR-644	miR-105, miR-124a, miR-135a, miR-189, miR-202, miR-219, miR-299-5p, miR-323, miR-379, miR-380-5p, miR-409-5p, miR-412, miR-512-3p, miR-566, miR-576, miR-600, miR-614, miR-616, miR-618, miR-631, miR-659, miR-31-5p, miR-192-3p, miR-194-5p, miR-551a, miR-551b-5p, miR-638, and miR-1290	[24, 25]
Addison’s disease	miR-181a_1	miR-200a_1, miR- 200a2	[26]
Sjogren’s syndrome	miR-146a-5p, miR-107, miR-222-3p, miR-324-3p, miR-18a-3p, miR-151a-3p, miR-107, miR-222-3p, miR-324-3p, miR-18a-3p, miR-151a-3p and others	miR-30b-5p, miR-582-5p, miR-30b-5p, miR-582-5p, and others	[27]
Systemic lupus erythematosus	miR-371b-5p, miR-5100, miR-4642, miR518b, miR-548ap-5p, miR-4762-5p, miR-767-3p, miR-4708-3p, and others	miR-148b-3p, miR-146a-5p, miR-451a, miR-223-3p, miR-1246, miR-21-5p, miR-30e-5p, and others	[28]
Rheumatoid arthritis	miR‐16, miR‐146a/b, miR‐155, miR‐150, miR‐223, miR-125b, miR-125a-5p, miR-146a, miR-146b, miR-203, miR-221, miR-222, and others	miR-34a, miR-34b, miR-124a, miR-125a-3p, miR-363, miR-498, miR-451, and others	[29]