Research Article

Imperatorin Suppresses Anaphylactic Reaction and IgE-Mediated Allergic Responses by Inhibiting Multiple Steps of FceRI Signaling in Mast Cells: IMP Alleviates Allergic Responses in PCA

Table 1

IMP alleviated anti-DNP IgE-mediated PCA.

GroupAmount of Evans blue (μg/g)

Con47.58±3.22
IgE+ Ag268.67±8.62
IgE+Ag+IMP (15mg/kg BW)235.33±6.69
IgE+Ag+IMP (30mg/kg BW)182.58±8.65#
IgE+Ag+IMP (60mg/kg BW)150.26±10.11##

Note: compared with the Con group, P<0.05; compared with the IgE+Ag group, #P<0.05, ##P<0.01. BW, body weight.