Research Article

Development and Validation of a Prediction Pneumothorax Model in CT-Guided Transthoracic Needle Biopsy for Solitary Pulmonary Nodule

Table 1

Clinical characteristics of the derivation cohort and the external validation cohort.

VariablesPneumothorax in the derivation cohortP valuePneumothorax in the validation cohortP value
No (n=256)Yes (n=55)No (n=176)Yes (n=51)

Sex, n (%)0.3930.881
 Female85 (33.20)15 (27.27)78 (44.32)22 (43.14)
 Male171 (66.80)40 (72.73)98 (55.68)29 (56.86)
Age, (years)59 (51-67)67 (60-72)<0.00161 (51-68)63 (58-73)0.016
Diagnosis of nodule, n (%)0.5520.314
 Benign69 (26.95)17 (30.91)86 (48.86)29 (56.86)
 Malignant187 (73.05)38 (69.09)90 (51.14)22 (43.14)
Nodule location, n (%)0.4950.776
 Non-periphery72 (28.12)18 (32.73)27 (15.34)7 (13.73)
 Periphery184 (71.88)37 (67.27)149 (84.66)44 (86.27)
Puncture position, (%)0.022<0.001
 Supine109 (42.58)20 (36.36)71 (40.34)5 (9.80)
 Prone130 (50.78)25 (45.45)74 (42.05)37 (72.55)
 Lateral17 ( 6.64)10 (18.18)31 (17.61)9 (17.65)
Nodule size, (mm)20.25 (17.50-24.50)20.50 (18.00-24.25)0.97020.00 (15.00-25.00)19.00 (15.00-25.00)0.607
Puncture distance, (mm)26.5 (19.0-40.0)32.0 (24.5-48.5)0.00215.0 (5.0-21.0)12.0 (5.0-20.0)0.374
Puncture times1 (1-1)1 (1-2)<0.0011 (1-2)2 (1-2)0.002