High Bone Mineral Density of the Lumbar Spine Is Positively Associated with Breast Cancer

Table 3

Odds Ratio (crude regression) between bone mineral density for menopausal status and breast cancer diagnosis. Goiânia. Brazil. 2014–2017.

	Total sample  (n = 376)				Premenopausal  (n = 175)				Postmenopausal  (n = 201)
	Not adjusted	p	Adjusted	p	Not adjusted	p	Adjusted	p	Not adjusted	p	Adjusted	p
	OR (IC95%)		OR (IC95%)		OR (IC95%)		OR (IC95%)		OR (IC95%)		OR (IC95%)
Lumbar spine (g/cm^2)
Q1 (lower)	1		1		1		1		1		1
Q2	0.83	0.540	1.51	0.285	0.72	0.458	2.79	0.140	0.86	0.71	1.73	0.380
	(0.46–1.50)		(0.71–3.23)		(0.31–1.70)		(0.71–10.91)		(0.39–1.89)	4	(0.51–5.94)
Q3	0.86	0.606	1.79	0.144	0.84	0.672	2.85	0.105	0.86	0.71	3.67	0.053
	(0.48–1.54)		(0.82–3.93)		(0.36–1.92)		(0.80–10.12)		(0.39–1.89)	4	(0.98–13.76)
Q4 (highest)	0.92	0.787	2.31	0.045	0.83	0.674	3.07	0.130	0.59	0.221	4.04	0.060
	(0.52–1.65)		(1.02–5.25)		(0.35–1.96)		(0.72–13.08)		(0.25–1.37)		(0.94–17.36)

The values are presented by odds ratio (OR) and p-value with a confidence interval of 95% (95% CI) and a significance level of 5%. The adjusted models were performed by the backward method (p < 0.20), and the variables for the lumbar spine correspond with the letters in the table as follows: (a) family history of breast cancer (1st degree), age, use of hormone replacement therapy, city of residence, years of education, family income/month, body mass index, and height; (b) level of physical activity, marital status, city of residence, early menarche, family income/month, height, waist circumference, total body weight, body mass index, and number of children born; (c) hormone replacement therapy, age of first late gestation, city of residence, schooling, family income/month, height, waist circumference, and body mass index. Femoral neck and total femur were not associated with the backward method and were automatically withdrawn from the adjusted analysis (p > 0.20).