Research Article

Study on miRNAs in Pan-Cancer of the Digestive Tract Based on the Illumina HiSeq System Data Sequencing

Table 4

GO function analysis of the 281 target genes ().

CategoryTermCount valueFold enrichment

GOTERM_BPGO:0030574∼collagen catabolic process84.16E − 058.463709677
GOTERM_BPGO:0001764∼neuron migration91.60E − 045.803686636
GOTERM_BPGO:0008284∼positive regulation of cell proliferation191.94E − 042.760695002
GOTERM_BPGO:0035987∼endodermal cell differentiation56.14E − 0412.53882915
GOTERM_BPGO:0048863∼stem cell differentiation56.14E − 0412.53882915
GOTERM_BPGO:0071560∼cellular response to transforming growth factor beta stimulus67.44E − 048.290980908
GOTERM_BPGO:0016477∼cell migration100.00102673.936609152
GOTERM_BPGO:0043410∼positive regulation of MAPK cascade70.00123225.851453604
GOTERM_BPGO:0043406∼positive regulation of MAP kinase activity60.00173386.885729907
GOTERM_BPGO:0010628∼positive regulation of gene expression120.00177733.101206599
GOTERM_BPGO:0010976∼positive regulation of neuron projection development70.0020025.325480246
GOTERM_BPGO:0030199∼collagen fibril organization50.00250858.680727874
GOTERM_BPGO:0010564∼regulation of cell cycle process30.003108833.85483871
GOTERM_BPGO:0007165∼signal transduction300.0036131.749604068
GOTERM_BPGO:0001666∼response to hypoxia90.00400093.542948237
GOTERM_BPGO:0031100∼organ regeneration50.0049647.203157172
GOTERM_BPGO:0010954∼positive regulation of protein processing30.005691325.39112903
GOTERM_BPGO:0060346∼bone trabecula formation30.005691325.39112903
GOTERM_BPGO:0002040∼sprouting angiogenesis40.005693210.83354839
GOTERM_BPGO:0030335∼positive regulation of cell migration90.00598843.311886396
GOTERM_BPGO:0050680∼negative regulation of epithelial cell proliferation50.00922626.045506912
GOTERM_CCGO:0005581∼collagen trimer83.46E − 046.071630851
GOTERM_CCGO:0045202∼synapse100.00119383.85766601
GOTERM_CCGO:0008076∼voltage-gated potassium channel complex70.00162475.554162313
GOTERM_CCGO:0005887∼integral component of plasma membrane350.00191261.727089341
GOTERM_CCGO:0005576∼extracellular region380.00259781.648014088
GOTERM_CCGO:0005886∼plasma membrane790.00330281.338528665
GOTERM_CCGO:0005925∼focal adhesion140.00419872.500083292
GOTERM_CCGO:0009986∼cell surface170.00501762.190043969
GOTERM_CCGO:0005578∼proteinaceous extracellular matrix110.00526242.865900383
GOTERM_CCGO:0031225∼anchored component of membrane70.00564574.325365341
GOTERM_CCGO:0030054∼cell junction150.00638332.281822052
GOTERM_CCGO:0030018∼Z disc70.00694464.142087149
GOTERM_CCGO:0044224∼juxtaparanode region of axon30.008460720.94712644
GOTERM_CCGO:0043197∼dendritic spine60.01429074.189425287
GOTERM_CCGO:0030424∼axon90.0146092.830692762
GOTERM_CCGO:0043025∼neuronal cell body110.01538542.43828985
GOTERM_CCGO:0005788∼endoplasmic reticulum lumen80.02050882.909323116
GOTERM_CCGO:0030425∼dendrite110.02253232.292720307
GOTERM_CCGO:0005923∼bicellular tight junction60.02299413.707456007
GOTERM_CCGO:0016324∼apical plasma membrane100.02422072.399441745
GOTERM_CCGO:0042383∼sarcolemma50.03338214.107279693
GOTERM_CCGO:0005588∼collagen type V trimer20.042195346.54916986
GOTERM_MFGO:0008201∼heparin binding119.92E − 054.815637967
GOTERM_MFGO:0005201∼extracellular matrix structural constituent60.00262796.272744163
GOTERM_MFGO:0004222∼metalloendopeptidase activity70.00553844.339110638
GOTERM_MFGO:0008083∼growth factor activity80.00852353.459044106
GOTERM_MFGO:0001948∼glycoprotein binding50.0137125.388126396
GOTERM_MFGO:0003779∼actin binding100.01820822.519627452
GOTERM_MFGO:0031683∼G-protein beta/gamma-subunit complex binding30.032321310.50684647
GOTERM_MFGO:0004114∼3′,5′-cyclic-nucleotide phosphodiesterase activity30.04186239.136388237
GOTERM_MFGO:0016167∼glial cell-derived neurotrophic factor receptor activity20.042050446.69709544
GOTERM_MFGO:0003707∼steroid hormone receptor activity40.04535085.003260225
GOTERM_MFGO:0005249∼voltage-gated potassium channel activity40.04946374.830734011