Research Article
Potential Diagnostic and Prognostic Biomarkers of Circular RNAs for Lung Cancer in China
Table 3
The results of the diagnostic analysis.
| | First author | Sensitivity | Specificity | LR+ (95%CI) | LR- (95%CI) | DOR | AUC |
| | Li JP | 0.76 (0.66-0.84) | 0.72 (0.68-0.84) | 2.69 (1.91-3.80) | 0.33 (0.23-0.49) | 8.08 (4.18-15.63) | | | Zhang YN | 0.80 (0.65-0.90) | 0.73 (0.58-0.85) | 3.00 (1.81-4.98) | 0.27 (0.15-0.50) | 11.00 (4.11-29.45) | | | Zhang SY | 0.87 (0.74-0.95) | 0.85 (0.71-0.94) | 5.71 (2.86-11.41) | 0.15 (0.07-0.33) | 37.14 (11.46-120.42) | | | Zhu XL | 0.76 (0.61-0.87) | 0.80 (0.66-0.90) | 3.70 (2.08-6.58) | 0.31 (0.18-0.51) | 12.02 (4.64-31.16) | | | Zong L | 0.81( 0.68-0.90) | 0.89 (0.78-0.96) | 7.67 (3.56-16.52) | 0.22 (0.13-0.37) | 35.55 (12.17-103.79) | | | Pooled | 0.80 (0.74-0.84) | 0.80 (0.73-0.86) | 3.97 (2.80-5.62) | 0.26 (0.19-0.34) | 15.51 (8.76-27.47) | 0.85 (0.82-0.88) | | I2 | 0 | 54.09% | 17.25% | 12.03% | 93.33% | |
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LR+: positive likelihood ratios; LR–, negative likelihood ratios; DOR, diagnostic odds ratios; AUC, area under curve; I2, inconsistency index.
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