STC2 Is a Potential Prognostic Biomarker for Pancreatic Cancer and Promotes Migration and Invasion by Inducing Epithelial–Mesenchymal Transition

Figure 2

STC2 was involved in the regulation of proliferation of pancreatic cancer cells. (a) The expression of STC2 was detected in several pancreatic cancer cell lines. GAPDH was used as a loading control. (b) The efficiency of overexpression or knock-down of STC2 was assessed in PANC-1 and HPAC cells. (c) CCK-8 assay was subjected to evaluate the proliferation rate with overexpression or knock-down of STC2 in PANC-1 (left panel in (b)) or HPAC cells (right panel in (b)). The respective cells without treatment were confined as control cells. P<0.05 was considered as significant difference, and one-way analysis of variance (ANOVA) was used to analyze the difference. The results were represented as the mean ± standard deviation (n = 3).

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