Diagnostic and Prognostic Values of BMPER in Patients with Urosepsis following Ureteroscopic Lithotripsy

Table 2

Parameters of patients with urosepsis 1 day after URSL.

Variable	Non urosepsis	Urosepsis	Uroseptic	P value
	(n=260)	(n=31)	Shock (n=14)
Age (years)	51.2 ± 7.5	51.7 ± 7.8	52.9 ± 5.1	0.735
Gender				0.535
Male	126	13	5
Female	134	18	9
DM (n)	17	11	4	<0.001
BMI	22.1 ± 6.4	23.4 ± 4.4	23.3 ± 4.0	0.518
Laterality				0.861
Left	134	15	8
Right	126	16	6
Stone site				0.137
Proximal	83	10	8
Middle	76	5	2
Distal	100	16	4
Stone size (mm)	7.6 ± 2.4	7.9 ± 3.7	7.7 ± 2.1	0.610
Hydronephrosis (cm)	2.1 ± 0.3	1.9 ± 0.4	2.3 ± 0.3	0.071
Irrigation pressure				0.006
Low-grade	104	7	1
Medium-grade	88	11	4
High-grade	68	13	10
Operation time (min)	23.7 ± 5.3	26.3 ± 4.0	29.0 ± 3.9	<0.001
WBC (10^9/L)	12.6 ± 3.1	15.4 ± 2.9	17.5 ± 3.9	<0.001
T	36.5 ± 0.08	39.2 ± 0.2	39.2 ± 0.2	<0.001
HR	77 ± 16	94 ± 8	92 ± 9	<0.001
MAP	90(80,101)	77(72,86)	64(60,66)	<0.001
PiO2/FiO2	402 ± 9	371 ± 56	359 ± 36	<0.001
PLT	213 ± 32	161 ± 51	145 ± 34	<0.001
CRP	12 ± 5	14 ± 2	24 ± 4	<0.001
PCT	1.32 ± 0.61	2.33 ± 1.14	3.60 ± 1.19	<0.001
BMPER	1.23 ± 0.52	1.62 ± 0.24	3.53 ± 0.77	<0.001
Cr	76 ± 16	154 ± 35	173 ± 33	<0.001
Serum albumin	37.3 ± 1.9	31.9 ± 3.2	31.6 ± 3.3	<0.001
Bilirubin	11.44(9.83,12.92)	22.68(16.04,29.22)	24.91(19.89,31.10)	<0.001
LAC	1.5(1.3,1.5)	1.6(1.4,1.8)	2.2(2.1,2.3)	<0.001

Kruskal-Wallis test. URSL: ureteroscopic lithotripsy; DM: diabetes mellitus; BMI: body mass index; T: temperature; HR: heart rate; MAP: mean arterial pressure; PLT: platelet; CRP: C-reactive protein; PCT: procalcitonin; BMPER: BMP-binding endothelial cell precursor-derived regulator; Cr: creatinine; LAC: lactate.