Irradiated Bladder Cancer Cells Expressing both GM-CSF and IL-21 versus Either GM-CSF or IL-21 Alone as Tumor Vaccine in a Mouse Xenograft Model

<p><i>Antitumor efficacy of GM-CSF/IL-21 vaccine</i>. (a, b) After establishing a metastatic mouse model of bladder cancer, therapeutic vaccines were injected into the mice at 0, 4, 8, and 12 days after xenograft tumor inoculation (<i>P</i> &lt; 0.05). (c, d) Tumor-specific cytotoxicity assay<i> in vitro </i>and<i> in vivo</i> (<i>P</i> &lt; 0.05).</p>

BioMed Research International

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Figure 2

Figure 2: Irradiated Bladder Cancer Cells Expressing both GM-CSF and IL-21 versus Either GM-CSF or IL-21 Alone as Tumor Vaccine in a Mouse Xenograft Model 

Figure 2 | Irradiated Bladder Cancer Cells Expressing both GM-CSF and IL-21 versus Either GM-CSF or IL-21 Alone as Tumor Vaccine in a Mouse Xenograft Model 