Optical Coherence Tomography of Animal Models of Retinitis Pigmentosa: From Animal Studies to Clinical Applications

Figure 7

Comparison of the SD-OCT, histological, and electron microscopic findings of RCS^–/– rats. (a) An SD-OCT image of an RCS^–/– rat on P26. (b) The histological appearance of an RCS^–/– rat on P25, indicating degeneration in the inner and outer segment zones of the photoreceptors. (c) The electron microscopic findings of the photoreceptor inner and outer segment layers of an RCS^–/– rat on P25 demonstrated accumulation of the extracellular lamellar materials (arrows). (d) The same layer in a wild-type RCS rat. White bar indicates 50 μm. Black bars indicate 5 μm.