MMP2 and MMP10 Polymorphisms Are Related to Steroid-Induced Osteonecrosis of the Femoral Head among Chinese Han Population
Table 2
Basic information of candidate SNPs in this study.
SNP
Gene
Position
Alleles
MAF
p value
ORs
95% CI
p value
A/B
case
control
for HWE
rs243866
MMP2
16q12.2
A/G
0.112
0.173
0.329
0.79
0.56
1.13
0.194
rs243864
MMP2
16q12.2
G/T
0.112
0.140
0.342
0.78
0.55
1.10
0.151
rs865094
MMP2
16q12.2
G/A
0.290
0.266
1.000
1.13
0.87
1.45
0.357
rs11646643
MMP2
16q12.2
G/A
0.175
0.205
0.601
0.83
0.62
1.11
0.202
rs2241146
MMP2
16q12.2
A/G
0.234
0.213
0.611
1.13
0.86
1.48
0.388
rs9928731
MMP2
16q12.2
T/C
0.486
0.476
0.170
1.04
0.83
1.31
0.719
rs470154
MMP10
11q22.2
T/G
0.149
0.107
1.000
1.45
1.03
2.05
0.032*
rs17293607
MMP10
11q22.2
G/A
0.003
0.005
1.000
0.72
0.12
4.32
0.931
SNP: single nucleotide polymorphism, HWE: Hardy-Weinberg equilibrium, OR: odds ratio, 95% CI: 95% confidence interval, and MAF: minor allele frequency. P values were calculated by exact test. P values were calculated by Pearson Chi-squared test.
