Higher Number of Night Shifts Associates with Good Perception of Work Capacity and Optimal Lung Function but Correlates with Increased Oxidative Damage and Telomere Attrition
Table 1
(a) Interval variables (mean ± SD) by level of work ability, according to WAI scores: 7-36 (poor-moderate), 37-43 (good), and 44-49 (excellent) in the study population.
Variables
Level of work ability
Poor-moderate n=57
Good n=85
Excellent n=13
Age (years)
48.7±5.7
47.9±6.2
44.7±4.9
Length of employment (years)
25.0±6.1
24.5±7.9
22.0±5.5
Length in the current job (years)
14.6±8.9
18.0±9.7
15.9±7.6
Education (years)
15.0±1.5
15.0±1.6
14.9±1.7
Body mass index (kg/m2)
27.2±6.1
25.4±4.6
24.0±3.6
Waist (cm)
99.2±13.7
96.0±12.0
93.8±7.7
Systolic pressure (mm Hg)
119.9±17.2
115.2±12.8
111.5±10.7
Diastolic pressure (mm Hg)
75.4±10.7
75.0±9.2
71.4±10.0
Mother age (years)
27.4±5.5
28.2±7.1
27.2±6.3
Father age (years)
30.1±5.2
31.8±7.0
29.9±6.1
Pack years [(cigarettes/20) x years]
7.7±10.1
6.9±10.4
10.2±10.5
Drinking (age at start, years)
13.0±11.3
13.5±11.8
17.2±10.7
Alcohol (daily intake last year)
0.2±0.3
0.2±0.4
0.3±0.8
Sport (IPAQ score)
3.2±3.4
3.4±2.3
2.8±2.1
Leukocytes (103/ml)
6.8±1.6
6.9±1.9
7.5±2.2
Blood red cells (103/ml)
4.6±0.6
4.7±0.4
4.6±0.5
Hemoglobin (g/dl)
12.8±1.4
13.3±1.4
13.7±1.6
Platelet count (103/ml)
282.4±71.6
279.6±63.8
247.7±51.9
Neutrophils (103/ml)
3.5±1.1
3.6±1.3
3.9±1.4
Lymphocytes (103/ml)
2.5±0.7
2.5±0.8
2.8±1.2
Monocytes (103/ml)
0.6±0.2
0.6±0.2
0.6±0.2
Eosinophils (103/ml)
0.2±0.1
0.2±0.1
0.2±0.1
Basophils (103/ml)
0.03±0.02
0.03±0.02
0.03±0.01
Glycaemia (mg/dl)
83.3±15.7
83.7±12.5
80.4±12.6
Cholesterol (mg/dl)
201.6±42.8
210.1±37.1
189.5±41.7
Triglycerides (mg/dl)
96.8±44.7
97.6±52.4
75.5±32.5
Low-density lipoprotein (mg/dl)
119.6±35.9
120.2±34.9
107.6±36.3
High-density lipoprotein (mg/dl)
65.4±19.2
69.9±16.6
66.8±15.1
C-reactive protein (mg/ml)
0.4±0.4
0.4±0.2
0.4±0.2
Glycated hemoglobin (mmol/mol)
36.4±7.0
36.5±7.4
32.0±5.8
Leukocyte telomere length (T/S)
1.1±0.2
1.1±0.2
1.0±0.2
FEV1 (liters)
2.8±0.5
2.9±0.6
3.5±0.7
FEV1 (% predicted)
105.7±15.8
108.4±11.9
113.6±19.9
Creatinine urine (μmol/mL)
9.4±4.7
10.0±5.1
10.6±6.2
8-oxoGuo (pmol/)
17.4±8.9
17.6±7.9
17.8±9.3
8-oxoGua (pmol/)
73.5±47.6
104.8±77.3
84.3±60.2
8-oxodGuo (pmol/)
8.4±5.0
9.3±5.2
11.4±7.5
7-MeGua (nmol/)
29.8±9.0
30.1±11.4
30.9±10.3
1-MeGua (pmol/)
887.5±1231.9
820.9±847.8
677.2±343.6
7-MeGuo (pmol/)
206.5±143.1
187.3±135.9
155.2±81.8
5-MeCyto (pmol/)
368.1±297.5
399.1±267.9
442.0±389.9
5-MeCyt (pmol/)
19.1±16.5
26.2±38.8
24.9±26.4
5-MedCyt (pmol/)
12.6±13.3
14.1±15.5
25.0±20.6
5-OHMeCyto (pmol/)
82.1±148.5
65.7±115.3
63.9±74.1
5-OHMedCyt (pmol/)
10.2±5.8
10.7±7.9
13.5±9.1
p-values (Kruskal–Wallis one-way analysis of variance): <0.05; = 0.002.
(b) Frequency variables (percentage) by level of work ability, according to WAI scores: 7-36 (poor-moderate), 37-43 (good), and 44-49 (excellent) in the study population. For dichotomous variable, table reports the percentage of individuals belonging to the class coded as 1.
