Research Article
Network Analyses of Differentially Expressed Genes in Osteoarthritis to Identify Hub Genes
Table 3
Signaling pathway enrichment analysis of DEGs function in osteoarthritis.
| | Expression | Term | Description | Gene Count | P Value |
| | DOWN-DEGs | hsa04923 | Regulation of lipolysis in adipocytes | 4 | 7.05E-04 | | hsa03320 | PPAR signaling pathway | 4 | 0.001191375 | | hsa04152 | AMPK signaling pathway | 4 | 0.006702552 | | hsa04910 | Insulin signaling pathway | 3 | 0.07107271 |
| | UP-DEGs | hsa04060 | Cytokine-cytokine receptor interaction | 8 | 1.22E-04 | | hsa04062 | Chemokine signaling pathway | 6 | 0.001756326 | | hsa05202 | Transcriptional misregulation in cancer | 5 | 0.007918451 | | hsa05323 | Rheumatoid arthritis | 4 | 0.008366703 | | hsa04668 | TNF signaling pathway | 4 | 0.014229192 | | hsa05322 | Systemic lupus erythematosus | 4 | 0.02575911 | | hsa05150 | Staphylococcus aureus infection | 3 | 0.027341561 |
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