Acute and Subacute Toxicity Studies of the Ethyl Acetate Soluble Proanthocyanidins of the Immature Inflorescence of Cocos nucifera L. in Female Wistar Rats

Table 1

Effect of EASPA on serum haematological parameters in acute toxicity study.

Parameters	Unit	Control	2000 mg/kg
WBC	10^9/L	6.10 ± 1.06	6.15 ± 0.53
RBC	10^12/L	7.48 ± 0.42	7.08 ± 0.08
Haemoglobin	g/dL	15.35 ± 0.83	14.45 ± 0.07
Haematocrit	%	43.2 ± 2.78	41.7 ± 0.42
MCV	fL	117.55 ± 0.72	117.9 ± 0.69
MCH	pg	20.0 ± 0.07	20.45 ± 0.32
MCHC	g/dL	34.1 ± 0.48	34.62 ± 0.62
PLT	10^9/L	912.25 ± 67.43	908.5 ± 48.73
Lymphocytes	10^9/L	5.65 ± 0.98	5.65 ± 0.50
Monocytes	10^9/L	0.3 ± 0.06	0.3 ± 0.03
Granules	10^9/L	0.15 ± 0.03	0.2 ± 0.00
RDW-CV	%	12.27 ± 0.23	12.4 ± 0.06
MPV	fL	12.0 ± 0.28	11.8 ± 0.33
PCT	%	0.57 ± 0.04	0.54 ±0.04

Values are expressed as a mean ± SEM ( and ).WBC: Total white blood cell count; RBC: total red blood cell count; PLT: platelet count; MCV: mean corpuscular volume; MCH: mean corpuscular haemoglobin; MCHC: mean corpuscular haemoglobin concentration; RDW-CV: red blood cell distribution width; MPV: mean platelet volume; PCT: procalcitonin.