Acute and Subacute Toxicity Studies of the Ethyl Acetate Soluble Proanthocyanidins of the Immature Inflorescence of Cocos nucifera L. in Female Wistar Rats
Table 5
Effect of EASPA on serum biochemical parameters in the subacute toxicity study.
Biochemical parameters
Unit
Control
1.75 mg/kg
3.5 mg/kg
7 mg/kg
14 mg/kg
ALP
U/L
226.83 ±15.14
246.50 ± 9.75
245.17 ± 3.00
244.00 ± 3.96
260.83 ± 5.59
ALT
U/L
72.31 ± 3.26
68.35 ± 4.05
70.08 ± 10.00
74.90 ± 12.23
64.55 ± 8.07
Glucose
mg/dL
75.24 ± 10.03
80.9 ± 10.28
83.12 ± 22.28
74.38 ± 7.48
82.06 ± 5.05
Cholesterol
mg/dL
62.95 ± 3.56
63.51 ± 1.78
64.16 ± 2.13
55.03 ± 0.99
60.08 ± 0.77
Urea
mmol/L
7.03 ± 0.48
5.91 ± 0.16
6.03 ± 0.14
6.32 ± 0.23
5.95 ± 0.23
Values are expressed as a mean ± SEM ( and ). (ALP: Serum alkaline phosphatase; ALT: serum alanine aminotransferase.)