Research Article
PEGylated Polyethylenimine Derivative-Mediated Local Delivery of the shSmad3 Inhibits Intimal Thickening after Vascular Injury
Figure 5
Effects of shSmad3 gene delivery on the expression of Col I, Col III, MMP1, MMP2, MMP9, and TIMP1. (a) qRT-PCR analysis Col I, Col III, MMP1, MMP2, MMP9, and TIMP1 mRNA expression, GAPDH served as internal standard. n = 3. (b) Western blot analysis of Col I, Col III, MMP1, MMP2, MMP9, and TIMP1 protein expression, GAPDH served as internal standard. Each bar shows as mean ± SD. P < 0.001.