Research Article
Positive Correlation between Activated CypA/CD147 Signaling and MMP-9 Expression in Mice Inflammatory Periapical Lesion
Table 1
Numbers of CypA+ Cells, CD147+ cells, and MMP-9+cells per high-power field ( 400) and percentage of osteoclasts, bone resorption volumes, and surface of periapical lesions (mean ± standard deviation).
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The greatest numbers of CypA +cells and CD147+ cells per high-power field appeared on day 28. The greatest percentage of MMP-9+ cells and osteoclasts reached on day 35. The greatest lesion volume appeared on day 42 and the greatest lesion surface appeared on day 49. Significant differences were found between day 0 and days 21, 28, 35, 42, and 49 and between day 7 and day 28 values of CypA+ cells. Statistical significance between groups was showed by tags. Positive correlation was found between lesion volume and surface and between numbers of CypA+ cells, CD147+ cells, MMP-9+ cells, and osteoclasts. hpf, high-power field. ԓPositive correlation (R2 = 0.5101, P < .01) with number of CypA + cells/hpf. ᴥPositive correlation (R2 =0.4423, P < .01) with number of CypA + cells/hpf. ⨲ Positive correlation (R2 = 0.4715, P < .01) with number of CypA + cells/hpf. фPositive correlation (R2 = 0.4053, P < .01) with lesion volume. ‡P < .05 versus 7-day group. ‖P < .05 versus 14-day group. §P < .05 versus 21-day group. фP < .05 versus 28-day group. ɣP < .05 versus 35-day group. ǂP < .05 versus 42-day group. ϮP < .05 versus 49-day group. †P < .05 versus 0-day group (control). |