Diagnostic and Predictive Value of Using RGD PET/CT in Patients with Cancer: A Systematic Review and Meta-Analysis

Table 3

Main characteristics of three studies for prediction of short-term outcome included in this meta-analysis.

Study	Country	Year	Number of Patients	Neoplasm	Sex; (M/F)	Mean Age	Imaging at Baseline	Study Design	Treatment	Response Criteria
Nadia Withofs [26]	Belgium	2015	32	Locally advanced rectal cancer	23/9	63 ± 8	^18F-FPRGD2 PET/CT	Prospective	CCRT	TRG; (0 VS. 1-3)
Hui Zhang [27]	China	2015	25	GBM after surgical resection	15/10	49.5 ± 19.5	^18F-alfatide RGD PET/CT	Prospective	CCRT	△; (cutoff=58%)
Xiaohui Luan [28]	China	2016	18	Advanced NSCLC	14/4	62 ± 12.04	^18F-alfatide RGD PET/CT	Prospective	CCRT	RECIST; (CR, PR VS. SD, PD)

△: the change of volume on MRI from baseline (T1) to the eleventh week (T3) after the start of CCRT. M/F: the ratio of male to female.