Tubulointerstitial Infiltration of M2 Macrophages in Henoch-Schönlein Purpura Nephritis Indicates the Presence of Glomerular Crescents and Bad Clinical Parameters

Figure 3

Area under curve (AUC) comparison of receiver operating characteristic (ROC) curves of tubulointerstitial M1 and M2 macrophage counts (a) and glomerular M1 and M2 macrophage counts (b) for the association with ISKDC classes III-IV. (a) AUC of tubulointerstitial M2 counts [0.778 (95% CI 0.637 to 0.884)] was wider than AUC of tubulointerstitial M1 counts [0.602 (95% CI 0.452 to 0.739)] (P=0.047). (b) AUC of glomerular M2 counts [0.804 (95% CI 0.666 to 0.904)] was wider than AUC of glomerular M1 counts [0.611 (95% CI 0.461 to 0.747)] (P=0.024). The AUC, 95% CI, and P-values in AUC comparison were obtained from DeLong method. ISKDC, International Study of Kidney Disease in Children; CI, confidence interval.

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