| | Class | Species | name | accession number | Protein length in amino acid(aa) | Signal Peptides | Position of IGFBP Domain | Position of VWC Domain | Position of TSP1 Domain | Position of CT Domain | Trans-membrane | Predicted positions of N-glycosylation |
| | Mammals | Homo sapiens | CCN1 | NP_001545 | 349 | 1-24 | 24 - 93 | 100 - 163 | 231 - 273 | 291 - 360 | 1-23 | - | | CCN2 | CAG46534 | 353 | 1-26 | 27 - 97 | 103 - 166 | 200 - 243 | 261 - 330 | 1-18 | 28 | | CCN3 | NP_002505 | 362 | 1-31 | 33 - 104 | 110 - 173 | 207 - 250 | 269 - 338 | 14-32 | 97 | | CCN4 | NP_003873 | 372 | 1-22 | 47 - 117 | 123 - 185 | 217 - 260 | 278 - 347 | 7-25,110-128,216-241 | 86,143 | | CCN5 | NP_001310299 | 253 | 1-23 | 24 - 93 | 100 - 163 | 194 - 238 | - | 199-217 | - | | CCN6 | NP_937882 | 377 | 1-33 | 64 - 134 | 140 - 197 | 229 - 271 | 291 - 360 | 21-37,158-176 | 196,326 | | Mus musculus | CCN1 | NP_034646 | 379 | 1-24 | 24 - 93 | 100 - 163 | 229 - 271 | 289 - 358 | 1-23 | - | | CCN2 | NP_034347 | 348 | 1-25 | 26 - 96 | 102 - 165 | 199 - 242 | 260 - 329 | 1-17 | - | | CCN3 | NP_035060 | 354 | 1-25 | 27 - 98 | 104 - 167 | 204 - 247 | 266 - 335 | 10-27 | 91,277 | | CCN4 | NP_061353 | 367 | 1-22 | 49 - 117 | 123 - 185 | 217 - 260 | 278 - 347 | 4-25,110-128 | 86,143,284 | | CCN5 | NP_058569 | 251 | 1-23 | 24 - 93 | 100 - 163 | 195 - 239 | - | 6-26,200-218 | - | | CCN6 | NP_001120848 | 354 | 1-19 | 46 - 116 | 122 - 179 | 211 - 253 | 273 - 342 | 1-19,140-157 | - |
| | Amphibian | Xenopus tropicalis | CCN1 | NP_001098984 | 375 | 1-24 | 24 - 93 | 100 - 163 | 226 - 268 | 286 - 355 | 3-24 | - | | CCN2 | NP_001015042 | 343 | 1-21 | 22 - 91 | 97 - 160 | 194 - 237 | 255 - 324 | 1-18 | - | | CCN3 | XP_002938019 | 344 | 1-18 | 19 - 89 | 95 - 158 | 191 - 234 | 253 - 322 | 1-19 | 264 | | CCN4 | XP_002939562 | 358 | 1-19 | 39 - 109 | 115 - 177 | 209 - 251 | 269 - 338 | 3-22,102-125,318-336 | 21,78,135 | | CCN5 | NP_001011237 | 312 | 1-23 | 24 - 92 | 98 - 161 | 190 - 234 | - | 4-26,195-213 | - | | CCN6 | XP_002936979 | 368 | - | 62 - 131 | 137 - 195 | 225 - 267 | 287 - 356 | - | - |
| | Bony fishes | Danio rerio | CCN1-c23 | NP_001001826 | 369 | 1-19 | 19 - 88 | 95 - 158 | 219 - 261 | 279 - 348 | 1-17 | 275 | | CCN1-c5 | NP_001017653 | 383 | 1-28 | 28 - 97 | 104 - 167 | 229 - 272 | 290 - 362 | 6-29 | - | | CCN1-c8 | NP_001074456 | 373 | 1-26 | 30 - 99 | 106 - 169 | 223 - 266 | 281 - 352 | 11-29 | 333 | | CCN2a | NP_001015041 | 345 | 1-23 | 24 - 93 | 99 - 162 | 196 - 239 | 257 - 326 | 2-18 | - | | CCN2b | NP_001096043 | 347 | 1-22 | 23 - 92 | 98 - 161 | 196 - 238 | 256 - 325 | 1-22 | - | | CCN4a | NP_001159702 | 360 | 1-19 | 44 - 114 | 120 - 182 | 212 - 255 | 273 - 342 | 1-18,325-344 | 41,155,279 | | CCN4b | NP_001107100 | 356 | 1-17 | 39 - 109 | 115 - 177 | 206 - 249 | 267 - 336 | 1-19 | 21,273 | | CCN5 | NP_001186030 | 344 | 1-28 | 29 - 98 | 104 - 167 | 203 - 246 | 265 - 334 | 13-31 | 228 | | CCN6 | NP_001159703 | 338 | 1-20 | 32 - 101 | 107 - 146 | 195 - 237 | 257 - 326 | 1-18,125-143 | - |
| | Agnatha | Lampetra japonica | CCN1I2 | ENSPMAG00000002981 | 387 | - | 24-94 | 101-167 | 235-278 | 298-366 | 5-23 | - | | CCN6 | ENSPMAG00000001225 | 370 | - | 46-116 | 122-185 | 221-263 | 281-350 | 286-306 | - | | ENSPMAG00000002439 | ENSPMAG00000002439 | 370 | - | 28-97 | 103-162 | 217-259 | 377-346 | - | - | | ENSPMAG00000008003 | ENSPMAG00000008003 | 174 | - | - | 3--67 | 128-171 | - | - | - |
| | Leptocardii | Amphioxus B. floridae | BRAFLDRAFT_276379 | XP_002600149 | 349 | 1-21 | 27 - 95 | 101 - 164 | 200 - 242 | 275 - 347 | 3-22,198-217 | - |
| | Ascidian | Ciona intestinalis | LOC100181891 | XP_002127157 | 374 | 1-23 | 33 - 101 | 107 - 171 | 227 - 270 | 288 - 356 | 3-21 | 179,180 | | LOC100176312 | XP_002131922 | 401 | - | 90 - 152 | 158 - 220 | 252 - 295 | 313 - 380 | 13-29,45-64 | - | | LOC100180049 | XP_018669063 | 428 | - | 26 - 96 | 102 - 166 | 274 - 317 | 335 - 406 | 5-27 | - | | LOC100183909 | XP_002130743 | 419 | - | 22 - 92 | 98 - 162 | 267 - 309 | 326 - 396 | 10-30 | - | | LOC100184755 | XP_002130917 | 207 | - | - | - | 59 - 99 | 118 - 188 | 25-46 | - |
| | Flies | Drosophila melanogaster | CCN | NP_730294 | 470 | 1-21 | - | 41 - 107 | 121 - 164 | - | 1-17 | 22,40,45,109,
120,126,365 |
| | Cestoda | Echinococcus multilocularis | CCN2 | CDI98339 | - | 1 22 | - | - | 100-143 | 192-264 | - | - |
| | Bivalvia | Crassostrea gigas | CCN2-like | XP_011420353 | 355 | 1 19 | 42 - 109 | 115 - 179 | 218 - 259 | 279 - 348 | 4-25 | 168,183,187,
212,259,288 |
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