Uterine Radial Artery Resistance Index Predicts Reproductive Outcome in Women with Recurrent Pregnancy Losses and Thrombophilia
Table 1
Age, BMI, number of miscarriages, and auto- and cellular immune profiles of the study group.
Characteristic
Total
Women with a live birth
Women with a miscarriage
P value
N
139
116
23
Mean age (yr)
34.9 ± 4.5
35.14±4.33
33.52±5.12
0.12
<40
114 (82.1%)
95(81.90)
19(82.61%)
0.94
≥40
25 (18.0%)
21(18.10%)
4(17.39%)
Mean BMI
25.2 ± 4.7
24.98±4.55
26.24±5.11
0.24
<19
2(1.4%)
1(0.86%)
1(4.35%)
0.15
≥19, <25
76 (54.7%)
67(57.76%)
9(39.13%)
≥25
61 (43.9%)
48(41.38%)
13(56.52%)
Number of miscarriages (n)
3.7 ± 1.6
3.59±1.52
4.13±1.74
0.14
<5
107 (77.0%)
92(79.31%)
15(65.22%)
0.18
≥5
32 (23.0%)
24(20.69%)
8(34.78%)
ANA
Negative
62 (44.6%)
54(46.55%)
8(34.78%)
0.36
Positive
77 (55.4%)
62(53.45%)
15(65.22%)
APA
Negative
69 (49.6%)
54(46.55%)
15(65.22%)
0.36
Positive
70 (50.4%)
62(53.45%)
8(34.78%)
CD56+NK cells
8.6 ± 4.7
8.38±4.70
9.56±4.92
0.21
<12%
108 (77.70%)
93(80.17%)
15(65.22)
0.17
≥12%
31 (22.30%)
23(19.83%)
8(34.78%)
NK cell cytotoxicity
E:T=50:1
16.35±6.50
15.77±6.00
19.24±8.11
0.02
E:T=25:1
11.02±5.31
10.59±5.02
13.20±6.27
0.03
E:T=12.5:1
7.05±4.19
6.71±3.95
8.53±4.91
0.06
TNF-α+/IL-10+ CD4+ T helper cell ratio
31.6 ± 10.1
31.62 ±10.30
31.46±9.03
0.80
<30.6
66(47.48%)
59(50.86%)
7(30.43%)
0.11
≥30.6
73 (52.52%)
57(49.14%)
16(69.57%)
IFN-γ+/IL-10+ CD4+ T helper cell ratio
15.7 ± 7.1
15.62 ±7.45
15.91±5.45
0.43
<20.5
108 (77.70%)
88(75.86%)
20(86.96%)
0.29
≥20.5
31 (22.30%)
28(24.14%)
3(13.04%)
Data expressed as mean± SD or a number with percentage. Body-mass index (BMI) is the weight in kilograms divided by the square of the height in meters (Kg/m2). Antinuclear antibody (ANA). Antiphospholipid antibodies (APA). Effector to target cell ratio (E:T).
