Analysis of the Relationship between Adult Asthma and Stroke: A Longitudinal Follow-Up Study Using the Korean National Sample Cohort
Table 3
Subgroup analysis of crude and adjusted hazard ratios (95% confidence interval) of asthma for hemorrhagic and ischemic stroke according to age and sex.
Characteristics
Hemorrhagic stroke
Ischemic stroke
Crude
p-value
Adjusted†
p-value
Crude
p-value
Adjusted†
p-value
Young men (20-39 years old, n = 22,396)
Asthma
0.90 (0.47-1.72)
0.739
0.88 (0.45-1.69)
0.689
0.70 (0.35-1.39)
0.305
0.69 (0.34-1.37)
0.282
Control
1.00
1.00
1.00
1.00
Young women (20-39 years old, n = 45,668)
Asthma
1.10 (0.61-1.98)
0.763
1.04 (0.58-1.89)
0.886
1.20 (0.66-2.17)
0.547
1.16 (0.64-2.10)
0.623
Control
1.00
1.00
1.00
1.00
Middle-aged men (40-59 years old, n = 32,316)
Asthma
0.96 (0.72-1.27)
0.774
0.94 (0.71-1.25)
0.674
0.79 (0.67-0.94)
0.006
0.76 (0.64-0.91)
0.002
Control
1.00
1.00
1.00
1.00
Middle-aged women (40-59 years old, n = 56,450)
Asthma
1.12 (0.89-1.42)
0.337
1.11 (0.88-1.40)
0.387
1.01 (0.85-1.21)
0.899
0.98 (0.82-1.17)
0.842
Control
1.00
1.00
1.00
1.00
Old men (60+ years old, n = 30,576)
Asthma
0.74 (0.62-0.90)
0.002
0.74 (0.62-0.89)
0.002
0.90 (0.82-0.98)
0.016
0.89 (0.81-0.97)
0.008
Control
1.00
1.00
1.00
1.00
Old women (60+ years old, n = 47,322)
Asthma
0.81 (0.70-0.94)
0.006
0.82 (0.70-0.95)
0.008
0.95 (0.88-1.02)
0.158
0.94 (0.87-1.01)
0.080
Control
1.00
1.00
1.00
1.00
Cox proportional hazards regression model, significance at p < 0.05. † Adjusted model for age, sex, income, region of residence, hypertension, diabetes, hyperlipidemia, ischemic heart disease, and depression histories.
